PTRF/cavin-1 remodels phospholipid metabolism to promote tumor proliferation and suppress immune responses in glioblastoma by stabilizing cPLA2

BACKGROUND: Metabolism remodeling is a hallmark of glioblastoma (GBM) that regulates tumor proliferation and the immune microenvironment. Previous studies have reported that increased polymerase 1 and transcript release factor (PTRF) levels are associated with a worse prognosis in glioma patients. H...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Yi, Kaikai, Zhan, Qi, Wang, Qixue, Tan, Yanli, Fang, Chuan, Wang, Yunfei, Zhou, Junhu, Yang, Chao, Li, Yansheng, Kang, Chunsheng
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Basic and Translational Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992898/
https://ncbi.nlm.nih.gov/pubmed/33140095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa255
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