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TGFβ signaling-induced miRNA participates in autophagic regulation by targeting PRAS40 in mesenchymal subtype of glioblastoma

Objective: Mesenchymal subtype of glioblastoma (mesGBM) is a refractory disease condition characterized by therapeutic failure and tumor recurrence. Hyperactive transforming growth factor-β (TGF-β) signaling could be a signature event in mesGBM, which leads to dysregulation of downstream targets and...

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Detalhes bibliográficos
Publicado no:Cancer Biol Med
Main Authors: Xie, Yingbin, Chen, Luyue, Zhou, Junhu, Yang, Chao, Xu, Can, Fan, Xiangyu, Tan, Yanli, Wang, Yanan, Kang, Chunsheng, Fang, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Compuscript 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476090/
https://ncbi.nlm.nih.gov/pubmed/32944398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2019.0356
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