A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma

Glioblastoma multiforme (GBMs) are recurrent lethal brain tumours. Recurrent GBMs often exhibit mesenchymal, stem-like phenotypes that could explain their resistance to therapy. Analyses revealed that recurrent GBMs have increased tension and express high levels of glycoproteins that increase the bu...

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書誌詳細
出版年:Nat Cell Biol
主要な著者: Barnes, J. Matthew, Kaushik, Shelly, Bainer, Russell O., Sa, Jason K., Woods, Elliot C., Kai, FuiBoon, Przybyla, Laralynne, Lee, Mijeong, Lee, Hye Won, Tung, Jason C., Maller, Ori, Barrett, Alexander S., Lu, Kan V., Lakins, Jonathon N., Hansen, Kirk C., Obernier, Kirsten, Alvarez-Buylla, Arturo, Bergers, Gabriele, Phillips, Joanna J., Nam, Do-Hyun, Bertozzi, Carolyn R., Weaver, Valerie M.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932748/
https://ncbi.nlm.nih.gov/pubmed/30202050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0183-3
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