TMIC-43. A TENSION-MEDIATED GLYCOCALYX FEEDBACK LOOP PROMOTES A MESENCHYMAL, STEM-LIKE PHENOTYPE IN GLIOBLASTOMA

Glioblastoma multiforme (GBM) is one of the deadliest central nervous system cancers, difficult to treat and largely impossible to cure. A considerable challenge in GBM therapy is treatment resistance and tumor recurrence, resulting in dismal patient prognosis. GBM aggression is often associated wit...

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Pubblicato in:Neuro Oncol
Autori principali: Kaushik, Shelly, Barnes, James Matthew, Bainer, Russell O, Sa, Jason K, Woods, Elliot C, Kai, FuiBoon, Przybyla, Laralynne, Lakins, Jonathon N, Phillips, Joanna J, Nam, Do-Hyun, Bertozzi, Carolyn R, Weaver, Valerie M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217080/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1102
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