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Tissue Mechanics Orchestrate Wnt-Dependent Human Embryonic Stem Cell Differentiation

Regenerative medicine is predicated on understanding the mechanisms regulating development and applying these conditions to direct stem cell fate. Embryogenesis is guided by cell-cell and cell-matrix interactions, but it is unclear how these physical cues influence stem cells in culture. We used hum...

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Publicado en:Cell Stem Cell
Autores principales: Przybyla, Laralynne, Lakins, Johnathon N., Weaver, Valerie M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336327/
https://ncbi.nlm.nih.gov/pubmed/27452175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.06.018
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