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Unmasked Brugada Pattern by Ajmaline Challenge in Patients with Myotonic Dystrophy Type 1

BACKGROUND: Myotonic dystrophy type 1 (DM1) generates missplicing of the SCN5A gene, encoding the cardiac sodium channel (Na(v)1.5). Brugada syndrome, which partly results from Na(v)1.5 dysfunction and causes increased VF occurrence, can be unmasked by ajmaline. We aimed to investigate the response...

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Dettagli Bibliografici
Pubblicato in:Ann Noninvasive Electrocardiol
Autori principali: Pambrun, Thomas, Bortone, Agustín, Bois, Patrick, Degand, Bruno, Patri, Sylvie, Mercier, Aurélie, Chahine, Mohamed, Chatelier, Aurélien, Coisne, Damien, Amiel, Alain
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6931494/
https://ncbi.nlm.nih.gov/pubmed/24943134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/anec.12168
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