Unmasked Brugada Pattern by Ajmaline Challenge in Patients with Myotonic Dystrophy Type 1

BACKGROUND: Myotonic dystrophy type 1 (DM1) generates missplicing of the SCN5A gene, encoding the cardiac sodium channel (Na(v)1.5). Brugada syndrome, which partly results from Na(v)1.5 dysfunction and causes increased VF occurrence, can be unmasked by ajmaline. We aimed to investigate the response...

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Detalhes bibliográficos
Publicado no:Ann Noninvasive Electrocardiol
Main Authors: Pambrun, Thomas, Bortone, Agustín, Bois, Patrick, Degand, Bruno, Patri, Sylvie, Mercier, Aurélie, Chahine, Mohamed, Chatelier, Aurélien, Coisne, Damien, Amiel, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6931494/
https://ncbi.nlm.nih.gov/pubmed/24943134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/anec.12168
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