Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma

The accumulation of lipids is a hallmark of human clear cell renal cell carcinoma (ccRCC). Advanced ccRCC tumors frequently show increased lipid biosynthesis, but the regulation of lipid metabolism in early stage ccRCC tumors has not been studied. Here, we performed combined transcriptomics and meta...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Transl Oncol
Prif Awduron: van der Mijn, Johannes C., Fu, Leiping, Khani, Francesca, Zhang, Tuo, Molina, Ana M., Barbieri, Christopher E., Chen, Qiuying, Gross, Steven S., Gudas, Lorraine J., Nanus, David M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press 2019
Pynciau:
Original article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6931219/
https://ncbi.nlm.nih.gov/pubmed/31865180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.10.015
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