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The Role of HIF1α in Renal Cell Carcinoma Tumorigenesis
The transcription factor HIF1α is implicated in the development of clear cell renal cell carcinoma (ccRCC). Although HIF1α was initially believed to be essential for ccRCC development, recent studies hypothesize an oncogenic role for HIF2α in ccRCC, but a tumor suppressor role for HIF1α [1], leading...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119538/ https://ncbi.nlm.nih.gov/pubmed/24916472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-014-1180-z |
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