Performance of the SAEM and FOCEI Algorithms in the Open‐Source, Nonlinear Mixed Effect Modeling Tool nlmixr

The free and open‐source package nlmixr implements pharmacometric nonlinear mixed effects model parameter estimation in R. It provides a uniform language to define pharmacometric models using ordinary differential equations. Performances of the stochastic approximation expectation‐maximization (SAEM...

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Vydáno v:CPT Pharmacometrics Syst Pharmacol
Hlavní autoři: Schoemaker, Rik, Fidler, Matthew, Laveille, Christian, Wilkins, Justin J., Hooijmaijers, Richard, Post, Teun M., Trame, Mirjam N., Xiong, Yuan, Wang, Wenping
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930853/
https://ncbi.nlm.nih.gov/pubmed/31654482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12471
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