Performance of the SAEM and FOCEI Algorithms in the Open‐Source, Nonlinear Mixed Effect Modeling Tool nlmixr

The free and open‐source package nlmixr implements pharmacometric nonlinear mixed effects model parameter estimation in R. It provides a uniform language to define pharmacometric models using ordinary differential equations. Performances of the stochastic approximation expectation‐maximization (SAEM...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Schoemaker, Rik, Fidler, Matthew, Laveille, Christian, Wilkins, Justin J., Hooijmaijers, Richard, Post, Teun M., Trame, Mirjam N., Xiong, Yuan, Wang, Wenping
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930853/
https://ncbi.nlm.nih.gov/pubmed/31654482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12471
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