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The somatic mutation landscape of the human body

BACKGROUND: Somatic mutations in healthy tissues contribute to aging, neurodegeneration, and cancer initiation, yet they remain largely uncharacterized. RESULTS: To gain a better understanding of the genome-wide distribution and functional impact of somatic mutations, we leverage the genomic informa...

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Publicat a:Genome Biol
Autors principals: García-Nieto, Pablo E., Morrison, Ashby J., Fraser, Hunter B.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930685/
https://ncbi.nlm.nih.gov/pubmed/31874648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1919-5
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