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The NF1 somatic mutational landscape in sporadic human cancers
BACKGROUND: Neurofibromatosis type 1 (NF1: Online Mendelian Inheritance in Man (OMIM) #162200) is an autosomal dominantly inherited tumour predisposition syndrome. Heritable constitutional mutations in the NF1 gene result in dysregulation of the RAS/MAPK pathway and are causative of NF1. The major k...
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| Publicado no: | Hum Genomics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5480124/ https://ncbi.nlm.nih.gov/pubmed/28637487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-017-0109-3 |
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