Lipophilicity Determination of Antifungal Isoxazolo[3,4-b]pyridin-3(1H)-ones and Their N1-Substituted Derivatives with Chromatographic and Computational Methods

The lipophilicity of a molecule is a well-recognized as a crucial physicochemical factor that conditions the biological activity of a drug candidate. This study was aimed to evaluate the lipophilicity of isoxazolo[3,4-b]pyridine-3(1H)-ones and their N1-substituted derivatives, which demonstrated pro...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Molecules
Päätekijät: Ciura, Krzesimir, Fedorowicz, Joanna, Andrić, Filip, Žuvela, Petar, Greber, Katarzyna Ewa, Baranowski, Paweł, Kawczak, Piotr, Nowakowska, Joanna, Bączek, Tomasz, Sączewski, Jarosław
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930598/
https://ncbi.nlm.nih.gov/pubmed/31779124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24234311
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia