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Characterization of antimicrobial and hemolytic properties of short synthetic cationic lipopeptides based on QSAR/QSTR approach

In this study, we investigated the influence of molecular descriptors of cationic lipopeptides on their antimicrobial activity and hemolytic properties. The quantitative structure–activity relationship and quantitative structure–property relationship models were constructed. The antimicrobial, hemol...

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Detalhes bibliográficos
Publicado no:Amino Acids
Main Authors: Greber, Katarzyna E., Ciura, Krzesimir, Belka, Mariusz, Kawczak, Piotr, Nowakowska, Joanna, Bączek, Tomasz, Sawicki, Wiesław
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852172/
https://ncbi.nlm.nih.gov/pubmed/29264738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-017-2530-2
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