Characterization of antimicrobial and hemolytic properties of short synthetic cationic lipopeptides based on QSAR/QSTR approach

In this study, we investigated the influence of molecular descriptors of cationic lipopeptides on their antimicrobial activity and hemolytic properties. The quantitative structure–activity relationship and quantitative structure–property relationship models were constructed. The antimicrobial, hemol...

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Veröffentlicht in:Amino Acids
Hauptverfasser: Greber, Katarzyna E., Ciura, Krzesimir, Belka, Mariusz, Kawczak, Piotr, Nowakowska, Joanna, Bączek, Tomasz, Sawicki, Wiesław
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Vienna 2017
Schlagworte:
Short Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852172/
https://ncbi.nlm.nih.gov/pubmed/29264738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-017-2530-2
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