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Cationic Net Charge and Counter Ion Type as Antimicrobial Activity Determinant Factors of Short Lipopeptides

To get a better insight into the antimicrobial potency of short cationic lipopeptides, 35 new entities were synthesized using solid phase peptide strategy. All newly obtained lipopeptides were designed to be positively charged from +1 to +4. This was achieved by introducing basic amino acid - lysine...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Greber, Katarzyna E., Dawgul, Malgorzata, Kamysz, Wojciech, Sawicki, Wieslaw
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285354/
https://ncbi.nlm.nih.gov/pubmed/28203232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00123
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