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Cationic Net Charge and Counter Ion Type as Antimicrobial Activity Determinant Factors of Short Lipopeptides

To get a better insight into the antimicrobial potency of short cationic lipopeptides, 35 new entities were synthesized using solid phase peptide strategy. All newly obtained lipopeptides were designed to be positively charged from +1 to +4. This was achieved by introducing basic amino acid - lysine...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Greber, Katarzyna E., Dawgul, Malgorzata, Kamysz, Wojciech, Sawicki, Wieslaw
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285354/
https://ncbi.nlm.nih.gov/pubmed/28203232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00123
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