Discovery of Selective Butyrylcholinesterase (BChE) Inhibitors through a Combination of Computational Studies and Biological Evaluations

As there are increased levels and activity of butyrylcholiesterase (BChE) in the late stage of Alzheimer’s disease (AD), development of selective BChE inhibitors is of vital importance. In this study, a workflow combining computational technologies and biological assays were implemented to identify...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Zhou, You, Lu, Xin, Yang, Hongyu, Chen, Yao, Wang, Feng, Li, Jifu, Tang, Zhiran, Cheng, Xifei, Yang, Yingbin, Xu, Li, Xia, Qingyou
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930573/
https://ncbi.nlm.nih.gov/pubmed/31757047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24234217
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares