Discovery of Selective Butyrylcholinesterase (BChE) Inhibitors through a Combination of Computational Studies and Biological Evaluations

As there are increased levels and activity of butyrylcholiesterase (BChE) in the late stage of Alzheimer’s disease (AD), development of selective BChE inhibitors is of vital importance. In this study, a workflow combining computational technologies and biological assays were implemented to identify...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Molecules
Egile Nagusiak: Zhou, You, Lu, Xin, Yang, Hongyu, Chen, Yao, Wang, Feng, Li, Jifu, Tang, Zhiran, Cheng, Xifei, Yang, Yingbin, Xu, Li, Xia, Qingyou
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930573/
https://ncbi.nlm.nih.gov/pubmed/31757047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24234217
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