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Tetrandrine Interaction with ABCB1 Reverses Multidrug Resistance in Cancer Cells Through Competition with Anti-Cancer Drugs Followed by Downregulation of ABCB1 Expression

The overexpression of ABC transporters induced by anticancer drugs has been found to be the main cause of multidrug resistance. It is actually also a strategy by which cancer cells escape being killed. Tetrandrine is a natural product extracted from the stem of Tinospora crispa. In this study, tetra...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Molecules
मुख्य लेखकों: Liao, Dan, Zhang, Wei, Gupta, Pranav, Lei, Zi-Ning, Wang, Jing-Quan, Cai, Chao-Yun, Vera, Albert A. De, Zhang, Lei, Chen, Zhe-Sheng, Yang, Dong-Hua
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930469/
https://ncbi.nlm.nih.gov/pubmed/31801248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24234383
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