Integrin-mediated Signaling via Paxillin-GIT1-PIX Promotes Localized Rac Activation at the Leading Edge and Cell Migration

Rac activation is precisely regulated temporally and spatially by intracellular signaling pathways in migrating cells to guarantee the formation of specific cell protrusions-lamellipodia at the leading edge. Integrins-mediated adhesions also control the signaling pathway for localized Rac activation...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cancer
Main Authors: Li, Youjun, Wu, Xinzhou, Liu, Zhiqiang, Lu, Kanghui, Liu, Rushi, Guo, Xiangrong
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2020
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930425/
https://ncbi.nlm.nih.gov/pubmed/31897230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.32853
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