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Silent Synapses Dictate Cocaine Memory Destabilization and Reconsolidation

Cocaine-associated memories are persistent, but, upon retrieval, become temporarily destabilized and vulnerable to disruptions, followed by reconsolidation. To explore the synaptic underpinnings for these memory dynamics, we studied AMPA receptor (AMPAR)-silent excitatory synapses, which are generat...

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Vydáno v:Nat Neurosci
Hlavní autoři: Wright, William J., Graziane, Nicholas M., Neumann, Peter A., Hamilton, Peter J., Cates, Hannah M., Fuerst, Lauren, Spenceley, Alexander, MacKinnon-Booth, Natalie, Iyer, Kartik, Huang, Yanhua H., Shaham, Yavin, Schlüter, Oliver M., Nestler, Eric J., Dong, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930359/
https://ncbi.nlm.nih.gov/pubmed/31792465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-019-0537-6
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