Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving

In rat models of drug relapse and craving, cue-induced cocaine seeking progressively increases after drug withdrawal. This ‘incubation of cocaine craving’ is partially mediated by time-dependent adaptations at glutamatergic synapses in nucleus accumbens. However, the circuit-level adaptations mediat...

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Bibliografiske detaljer
Main Authors: Lee, Brian R., Ma, Yao-ying, Huang, Yanhua H., Wang, Xiusong, Otaka, Mami, Ishikawa, Masago, Neumann, Peter A., Graziane, Nicolas M., Brown, Travis E., Suska, Anna, Guo, Changyong, Lobo, Mary Kay, Sesack, Susan R., Wolf, Marina E., Nestler, Eric J., Shaham, Yavin, Schlüter, Oliver M., Dong, Yan
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815713/
https://ncbi.nlm.nih.gov/pubmed/24077564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3533
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