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Bi-directional modulation of incubation of cocaine craving by silent synapse-based remodeling of prefrontal cortex to accumbens projections
Glutamatergic projections from the medial prefrontal cortex (mPFC) to nucleus accumbens (NAc) contribute to cocaine relapse. Here we show that silent synapse-based remodeling of the two major mPFC-to-NAc projections differentially regulated the progressive increase in cue-induced cocaine seeking aft...
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| Udgivet i: | Neuron |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4295617/ https://ncbi.nlm.nih.gov/pubmed/25199705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.08.023 |
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