Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving

In rat models of drug relapse and craving, cue-induced cocaine seeking progressively increases after drug withdrawal. This ‘incubation of cocaine craving’ is partially mediated by time-dependent adaptations at glutamatergic synapses in nucleus accumbens. However, the circuit-level adaptations mediat...

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Autores principales: Lee, Brian R., Ma, Yao-ying, Huang, Yanhua H., Wang, Xiusong, Otaka, Mami, Ishikawa, Masago, Neumann, Peter A., Graziane, Nicolas M., Brown, Travis E., Suska, Anna, Guo, Changyong, Lobo, Mary Kay, Sesack, Susan R., Wolf, Marina E., Nestler, Eric J., Shaham, Yavin, Schlüter, Oliver M., Dong, Yan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815713/
https://ncbi.nlm.nih.gov/pubmed/24077564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3533
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