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Opposing mechanisms mediate morphine- and cocaine-induced generation of silent synapses
Exposures to cocaine and morphine produce similar adaptations in nucleus accumbens (NAc)-based behaviors, yet produce very different adaptations at NAc excitatory synapses. Here, we explain this paradox by showing that both drugs induce NMDA receptor-containing, AMPA receptor (AMPAR)-silent excitato...
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| Publicado no: | Nat Neurosci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4925174/ https://ncbi.nlm.nih.gov/pubmed/27239940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4313 |
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