Restricted Myeloperoxidase Epitopes Drive the Adaptive Immune Response in MPO ANCA Vasculitis

BACKGROUND: Treatment of autoimmune diseases has relied on broad immunosuppression. Knowledge of specific interactions between human leukocyte antigen (HLA), the autoantigen, and effector immune cells, provides the foundation for antigen-specific therapies. These studies investigated the role of HLA...

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Publicado en:J Autoimmun
Autores principales: Free, Meghan E., Stember, Katherine G., Hess, Jacob J., McInnis, Elizabeth A., Lardinois, Olivier, Hogan, Susan L., Hu, Yichun, Mendoza, Carmen, Le, Andrew K., Guseman, Alex J., Pilkinton, Mark A., Bortone, Dante S., Cowens, Kristen, Sidney, John, Karosiene, Edita, Peters, Bjoern, James, Eddie, Kwok, William W., Vincent, Benjamin G., Mallal, Simon A., Jennette, J. Charles, Ciavatta, Dominic J., Falk, Ronald J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930338/
https://ncbi.nlm.nih.gov/pubmed/31383567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2019.102306
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