Dysregulation of Autoantigen Genes in ANCA-Associated Vasculitis Involves Alternative Transcripts and New Protein Synthesis

Proteinase 3 (PR3) and myeloperoxidase (MPO) are two major autoantigens in patients with vasculitis with ANCA. The genes encoding these autoantigens are abnormally expressed in peripheral granulocytes of patients with active ANCA-associated vasculitis. This study provides evidence that this transcri...

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Библиографические подробности
Опубликовано в: :J Am Soc Nephrol
Главные авторы: McInnis, Elizabeth A., Badhwar, Anshul K., Muthigi, Akhil, Lardinois, Olivier M., Allred, S. Colby, Yang, Jiajin, Free, Meghan E., Jennette, J. Charles, Preston, Gloria A., Falk, Ronald J., Ciavatta, Dominic J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2015
Предметы:
Basic Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310652/
https://ncbi.nlm.nih.gov/pubmed/25060059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013101092
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