Dysregulation of Autoantigen Genes in ANCA-Associated Vasculitis Involves Alternative Transcripts and New Protein Synthesis

Proteinase 3 (PR3) and myeloperoxidase (MPO) are two major autoantigens in patients with vasculitis with ANCA. The genes encoding these autoantigens are abnormally expressed in peripheral granulocytes of patients with active ANCA-associated vasculitis. This study provides evidence that this transcri...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Am Soc Nephrol
Auteurs principaux: McInnis, Elizabeth A., Badhwar, Anshul K., Muthigi, Akhil, Lardinois, Olivier M., Allred, S. Colby, Yang, Jiajin, Free, Meghan E., Jennette, J. Charles, Preston, Gloria A., Falk, Ronald J., Ciavatta, Dominic J.
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2015
Sujets:
Basic Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310652/
https://ncbi.nlm.nih.gov/pubmed/25060059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013101092
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires