Dysregulation of Autoantigen Genes in ANCA-Associated Vasculitis Involves Alternative Transcripts and New Protein Synthesis

Proteinase 3 (PR3) and myeloperoxidase (MPO) are two major autoantigens in patients with vasculitis with ANCA. The genes encoding these autoantigens are abnormally expressed in peripheral granulocytes of patients with active ANCA-associated vasculitis. This study provides evidence that this transcri...

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Detaylı Bibliyografya
Yayımlandı:J Am Soc Nephrol
Asıl Yazarlar: McInnis, Elizabeth A., Badhwar, Anshul K., Muthigi, Akhil, Lardinois, Olivier M., Allred, S. Colby, Yang, Jiajin, Free, Meghan E., Jennette, J. Charles, Preston, Gloria A., Falk, Ronald J., Ciavatta, Dominic J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2015
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310652/
https://ncbi.nlm.nih.gov/pubmed/25060059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013101092
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