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PI3Kα in cardioprotection: Cytoskeleton, late Na(+) current, and mechanism of arrhythmias

PI 3-kinase α (PI3Kα) is a lipid kinase that converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-triphosphate (PIP3). PI3Kα regulates a variety of cellular processes such as nutrient sensing, cell cycle, migration, and others. Heightened activity of PI3Kα in many type...

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Detalhes bibliográficos
Publicado no:Channels (Austin)
Main Authors: Zhabyeyev, Pavel, Chen, Xueyi, Vanhaesebroeck, Bart, Oudit, Gavin Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930018/
https://ncbi.nlm.nih.gov/pubmed/31790629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2019.1697127
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