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Endothelial and cardiomyocyte PI3Kβ divergently regulate cardiac remodelling in response to ischaemic injury

AIMS: Cardiac remodelling in the ischaemic heart determines prognosis in patients with ischaemic heart disease (IHD), while enhancement of angiogenesis and cell survival has shown great potential for IHD despite translational challenges. Phosphoinositide 3-kinase (PI3K)/Akt signalling pathways play...

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Bibliografiske detaljer
Udgivet i:Cardiovasc Res
Main Authors: Chen, Xueyi, Zhabyeyev, Pavel, Azad, Abul K, Wang, Wang, Minerath, Rachel A, DesAulniers, Jessica, Grueter, Chad E, Murray, Allan G, Kassiri, Zamaneh, Vanhaesebroeck, Bart, Oudit, Gavin Y
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587920/
https://ncbi.nlm.nih.gov/pubmed/30496354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy298
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