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Alzheimer’s disease pathology is attenuated in a CD38 deficient mouse model
OBJECTIVE: Alzheimer’s disease (AD) associated dementia is due to tissue damage caused by amyloid β (Aβ) deposition within the brain and by accompanying neuroinflammation. The NAD glycohydrolase, CD38, which is expressed by neurons, astrocytes and microglial cells, regulates inflammatory and repair...
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| Publicado no: | Ann Neurol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6929692/ https://ncbi.nlm.nih.gov/pubmed/25893674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24425 |
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