Alzheimer’s disease pathology is attenuated in a CD38 deficient mouse model

OBJECTIVE: Alzheimer’s disease (AD) associated dementia is due to tissue damage caused by amyloid β (Aβ) deposition within the brain and by accompanying neuroinflammation. The NAD glycohydrolase, CD38, which is expressed by neurons, astrocytes and microglial cells, regulates inflammatory and repair...

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Bibliografiset tiedot
Julkaisussa:Ann Neurol
Päätekijät: Blacher, Eran, Dadali, Tulin, Bespalko, Alina, Haupenthal, Viola J, Grimm, Marcus O. W., Hartmann, Tobias, Lund, Frances E., Stein, Reuven, Levy, Ayelet
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929692/
https://ncbi.nlm.nih.gov/pubmed/25893674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24425
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