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DDI-PULearn: a positive-unlabeled learning method for large-scale prediction of drug-drug interactions

BACKGROUND: Drug-drug interactions (DDIs) are a major concern in patients’ medication. It’s unfeasible to identify all potential DDIs using experimental methods which are time-consuming and expensive. Computational methods provide an effective strategy, however, facing challenges due to the lack of...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Zheng, Yi, Peng, Hui, Zhang, Xiaocai, Zhao, Zhixun, Gao, Xiaoying, Li, Jinyan
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929327/
https://ncbi.nlm.nih.gov/pubmed/31870276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3214-6
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