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Positive-unlabeled learning for the prediction of conformational B-cell epitopes

BACKGROUND: The incomplete ground truth of training data of B-cell epitopes is a demanding issue in computational epitope prediction. The challenge is that only a small fraction of the surface residues of an antigen are confirmed as antigenic residues (positive training data); the remaining residues...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Ren, Jing, Liu, Qian, Ellis, John, Li, Jinyan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682424/
https://ncbi.nlm.nih.gov/pubmed/26681157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S18-S12
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