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Benzo[b]tellurophenes as a Potential Histone H3 Lysine 9 Demethylase (KDM4) Inhibitor

Gene expression and tumor growth can be regulated by methylation levels of lysine residues on histones, which are controlled by histone lysine demethylases (KDMs). Series of benzo[b]tellurophene and benzo[b]selenophene compounds were designed and synthesized and they were evaluated for histone H3 ly...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Yoon-Jung, Lee, Dong Hoon, Choi, Yong-Sung, Jeong, Jin-Hyun, Kwon, So Hee
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928947/
https://ncbi.nlm.nih.gov/pubmed/31775247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20235908
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