A Potent Autophagy Inhibitor (Lys05) Enhances the Impact of Ionizing Radiation on Human Lung Cancer Cells H1299

Autophagy inhibition through small-molecule inhibitors is one of the approaches to increase the efficiency of radiotherapy in oncological patients. A new inhibitor—Lys05—with the potential to accumulate within lysosomes and to block autophagy was discovered a few years ago. Several studies have addr...

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Опубликовано в: :Int J Mol Sci
Главные авторы: Cechakova, Lucie, Ondrej, Martin, Pavlik, Vojtech, Jost, Petr, Cizkova, Dana, Bezrouk, Ales, Pejchal, Jaroslav, Amaravadi, Ravi K., Winkler, Jeffrey D., Tichy, Ales
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928878/
https://ncbi.nlm.nih.gov/pubmed/31771188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20235881
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