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Cutaneous pharmacologic cAMP induction induces melanization of the skin and improves recovery from ultraviolet injury in melanocortin 1 receptor-intact or heterozygous skin

Homozygous loss of function of the melanocortin 1 receptor (MC1R) is associated with a pheomelanotic pigment phenotype and increased melanoma risk. MC1R heterozygosity is less well studied, although individuals inheriting one loss-of-function MC1R allele are also melanoma-prone. Using the K14-Scf C5...

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Detalhes bibliográficos
Publicado no:Pigment Cell Melanoma Res
Main Authors: Bautista, Robert-Marlo Felicilda, Carter, Katharine Marie, Jarrett, Stuart Gordon, Napier, Dana, Wakamatsu, Kazumasa, Ito, Shosuke, D’Orazio, John August
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928432/
https://ncbi.nlm.nih.gov/pubmed/31398282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12817
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