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Purification and growth of melanocortin 1 receptor (Mc1r)-defective primary murine melanocytes is dependent on stem cell factor from keratinocyte-conditioned media

The melanocortin 1 receptor (MC1R) is a transmembrane G(s)-coupled surface protein found on melanocytes that binds melanocyte stimulating hormone (MSH) and mediates activation of adenylyl cyclase and generation of the second messenger cAMP. MC1R regulates growth and differentiation of melanocytes an...

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Detalhes bibliográficos
Publicado no:In Vitro Cell Dev Biol Anim
Principais autores: Scott, Timothy L., Wakamatsu, Kazumasa, Ito, Shosuke, D’Orazio, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356244/
https://ncbi.nlm.nih.gov/pubmed/19633898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11626-009-9232-3
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