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Purification and growth of melanocortin 1 receptor (Mc1r)-defective primary murine melanocytes is dependent on stem cell factor from keratinocyte-conditioned media
The melanocortin 1 receptor (MC1R) is a transmembrane G(s)-coupled surface protein found on melanocytes that binds melanocyte stimulating hormone (MSH) and mediates activation of adenylyl cyclase and generation of the second messenger cAMP. MC1R regulates growth and differentiation of melanocytes an...
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Publicado no: | In Vitro Cell Dev Biol Anim |
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Principais autores: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4356244/ https://ncbi.nlm.nih.gov/pubmed/19633898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11626-009-9232-3 |
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