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Purification and growth of melanocortin 1 receptor (Mc1r)-defective primary murine melanocytes is dependent on stem cell factor from keratinocyte-conditioned media

The melanocortin 1 receptor (MC1R) is a transmembrane G(s)-coupled surface protein found on melanocytes that binds melanocyte stimulating hormone (MSH) and mediates activation of adenylyl cyclase and generation of the second messenger cAMP. MC1R regulates growth and differentiation of melanocytes an...

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Detalles Bibliográficos
Publicado en:In Vitro Cell Dev Biol Anim
Main Authors: Scott, Timothy L., Wakamatsu, Kazumasa, Ito, Shosuke, D’Orazio, John A.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356244/
https://ncbi.nlm.nih.gov/pubmed/19633898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11626-009-9232-3
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