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Regulation of eumelanin / pheomelanin synthesis and visible pigmentation in melanocytes by ligands of the melanocortin 1 receptor

The production of melanin in the hair and skin is tightly regulated by the melanocortin 1 receptor (MC1R) whose activation is controlled by 2 secreted ligands, α-melanocyte stimulating hormone (αMSH) and agouti signal protein (ASP). Since melanin is extremely stable, lasting years in biological tiss...

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Detalhes bibliográficos
Main Authors: Le Pape, Elodie, Wakamatsu, Kazumasa, Ito, Shosuke, Wolber, Rainer, Hearing, Vincent J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562678/
https://ncbi.nlm.nih.gov/pubmed/18627531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2008.00479.x
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