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Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes

Sideroflexin4 (SFXN4) is a member of a family of nuclear-encoded mitochondrial proteins. Rare germline mutations in SFXN4 lead to phenotypic characteristics of mitochondrial disease including impaired mitochondrial respiration and hematopoetic abnormalities. We sought to explore the function of this...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Paul, Bibbin T., Tesfay, Lia, Winkler, C. R., Torti, Frank M., Torti, Suzy V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928202/
https://ncbi.nlm.nih.gov/pubmed/31873120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55907-z
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