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SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors
Growth and patterning of the cerebellum is compromised if granule cell precursors do not properly expand and migrate. During embryonic and postnatal cerebellar development, the Hedgehog pathway tightly regulates granule cell progenitors to coordinate appropriate foliation and lobule formation. Indee...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6928071/ https://ncbi.nlm.nih.gov/pubmed/31873117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56057-y |
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