VEGF/VEGFR2 signaling regulates hippocampal axon branching during development

Axon branching is crucial for proper formation of neuronal networks. Although originally identified as an angiogenic factor, VEGF also signals directly to neurons to regulate their development and function. Here we show that VEGF and its receptor VEGFR2 (also known as KDR or FLK1) are expressed in m...

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Detalhes bibliográficos
Publicado no:eLife
Principais autores: Luck, Robert, Urban, Severino, Karakatsani, Andromachi, Harde, Eva, Sambandan, Sivakumar, Nicholson, LaShae, Haverkamp, Silke, Mann, Rebecca, Martin-Villalba, Ana, Schuman, Erin Margaret, Acker-Palmer, Amparo, Ruiz de Almodóvar, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927742/
https://ncbi.nlm.nih.gov/pubmed/31868583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49818
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