VEGF/VEGFR2 signaling regulates hippocampal axon branching during development

Axon branching is crucial for proper formation of neuronal networks. Although originally identified as an angiogenic factor, VEGF also signals directly to neurons to regulate their development and function. Here we show that VEGF and its receptor VEGFR2 (also known as KDR or FLK1) are expressed in m...

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Vydáno v:eLife
Hlavní autoři: Luck, Robert, Urban, Severino, Karakatsani, Andromachi, Harde, Eva, Sambandan, Sivakumar, Nicholson, LaShae, Haverkamp, Silke, Mann, Rebecca, Martin-Villalba, Ana, Schuman, Erin Margaret, Acker-Palmer, Amparo, Ruiz de Almodóvar, Carmen
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927742/
https://ncbi.nlm.nih.gov/pubmed/31868583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49818
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