Mutant p53 drives cancer chemotherapy resistance due to loss of function on activating transcription of PUMA

P53 is a critical tumor suppressor gene, activating p53 and its downstream targets to induce apoptosis is a promising way for cancer therapy. However, more than 50% of cancer patients have p53 mutations, which may cause cancer therapy resistance, and the underline mechanism is poorly understood. Her...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Huang, Yuan, Liu, Nannan, Liu, Jing, Liu, Yeying, Zhang, Chuchu, Long, Shuaiyu, Luo, Guang, Zhang, Lingling, Zhang, Yingjie
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927701/
https://ncbi.nlm.nih.gov/pubmed/31726940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1688951
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados