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Common polymorphisms of CYP2B6 influence stereoselective bupropion disposition
Bupropion hydroxylation is a bioactivation and metabolic pathway, and the standard clinical CYP2B6 probe. This investigation determined the influence of CYP2B6 allelic variants on clinical concentrations and metabolism of bupropion enantiomers. Secondary objectives evaluated the influence of CYP2C19...
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| Publicado en: | Clin Pharmacol Ther |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6927671/ https://ncbi.nlm.nih.gov/pubmed/29756345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1116 |
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