BMPR2 acts as a gatekeeper to protect endothelial cells from increased TGFβ responses and altered cell mechanics

Balanced transforming growth factor-beta (TGFβ)/bone morphogenetic protein (BMP)-signaling is essential for tissue formation and homeostasis. While gain in TGFβ signaling is often found in diseases, the underlying cellular mechanisms remain poorly defined. Here we show that the receptor BMP type 2 (...

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Detaylı Bibliyografya
Yayımlandı:PLoS Biol
Asıl Yazarlar: Hiepen, Christian, Jatzlau, Jerome, Hildebrandt, Susanne, Kampfrath, Branka, Goktas, Melis, Murgai, Arunima, Cuellar Camacho, Jose Luis, Haag, Rainer, Ruppert, Clemens, Sengle, Gerhard, Cavalcanti-Adam, Elisabetta Ada, Blank, Kerstin G., Knaus, Petra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927666/
https://ncbi.nlm.nih.gov/pubmed/31826007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000557
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