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Alterations of the interactome of Bcl-2 proteins in breast cancer at the transcriptional, mutational and structural level
Apoptosis is an essential defensive mechanism against tumorigenesis. Proteins of the B-cell lymphoma-2 (Bcl-2) family regulate programmed cell death by the mitochondrial apoptosis pathway. In response to intracellular stress, the apoptotic balance is governed by interactions of three distinct subgro...
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| Publicat a: | PLoS Comput Biol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6927658/ https://ncbi.nlm.nih.gov/pubmed/31825969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007485 |
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