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Secreted breast tumor interstitial fluid microRNAs and their target genes are associated with triple-negative breast cancer, tumor grade, and immune infiltration

BACKGROUND: Studies on tumor-secreted microRNAs point to a functional role of these in cellular communication and reprogramming of the tumor microenvironment. Uptake of tumor-secreted microRNAs by neighboring cells may result in the silencing of mRNA targets and, in turn, modulation of the transcrip...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Terkelsen, Thilde, Russo, Francesco, Gromov, Pavel, Haakensen, Vilde Drageset, Brunak, Søren, Gromova, Irina, Krogh, Anders, Papaleo, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329449/
https://ncbi.nlm.nih.gov/pubmed/32605588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-01295-6
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