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Wnt Signaling and Its Significance Within the Tumor Microenvironment: Novel Therapeutic Insights

Wnt signaling is one of the central mechanisms regulating tissue morphogenesis during embryogenesis and repair. The pivot of this signaling cascade is the Wnt ligand, which binds to receptors belonging to the Frizzled family or the ROR1/ROR2 and RYK family. This interaction governs the downstream si...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Patel, Sonal, Alam, Aftab, Pant, Richa, Chattopadhyay, Samit
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927425/
https://ncbi.nlm.nih.gov/pubmed/31921137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02872
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